Methionine and vitamin B-complex ameliorate antitubercular drugs-induced toxicity in exposed patients
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چکیده
منابع مشابه
Methionine and vitamin B‐complex ameliorate antitubercular drugs‐induced toxicity in exposed patients
Tuberculosis therapy utilizes drugs that while effective cause treatment-related toxicity. Modulation of antitubercular drugs-induced toxicity by methionine and vitamin B-complex in patients was evaluated. 285 treatment-naïve tuberculosis patients at the Chest Clinics of Infectious Diseases Hospital, Yaba and General Hospital, Lagos in Lagos, Nigeria was prospectively recruited and allotted int...
متن کاملORGANOPHOSPHATE-INDUCED CHRONIC TOXICITY IN OCCUPATIONALLY EXPOSED WORKERS
Organophosphate chronic toxicity has been evaluated in this study. Biological screening for organophosphate insecticide-exposed workers is mostly recommended for mixers, loaders, formulators and spraymen. We have studied 17 occupationally exposed persons to pesticides. Using Ellman's colorimetric method, their plasma cholinesterase activities have been measured. Results show that the appear...
متن کاملB-vitamin deficiency in patients treated with antiepileptic drugs.
Enzyme-inducing antiepileptic drugs (AEDs) produce many alterations in metabolism, including vitamin levels. Whether they produce clinically relevant deficiency of B vitamins has rarely been assessed. We obtained B-vitamin levels in patients who were being converted from an inducing AED (phenytoin or carbamazepine) to a non-inducing AED (levetiracetam, lamotrigine, or topiramate), with measurem...
متن کاملFasting and post-methionine loading concentrations of homocysteine, vitamin B2, and vitamin B6 in patients on antiepileptic drugs.
Paediatr Suppl 1999;88:200–8. 21. Wajnrajch MP, Gertner JM, Mullis PE, Deladoëy J, Cogan JD, Lekhakula S, et al. ARGHIS is a new mutational “hot-spot” in the growth hormone (GH) gene causing isolated GH deficiency type II. J Endocr Genet 2001;1:125– 35. 22. Wada M, Uchida H, Ikeda M, Tsunekawa B, Naito N, Banba S, et al. The 20-kilodalton (kDA) human growth hormone (hGH) differs from the 22-kDA...
متن کاملThe Vitamin B Complex
died) ; and that Michael made excellent attempts to isolate the antiscorbutic principle early in the eighteenth century. Further, Lunin (1881) clearly recognized that small quantities of unknown substances were essential to life, and Pekelharing (1905) demonstrated the existence of diseases due to dietary deficiency. Yet it was Hopkins (1912) who first realized the full significance of vitamins...
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ژورنال
عنوان ژورنال: Pharmacology Research & Perspectives
سال: 2017
ISSN: 2052-1707
DOI: 10.1002/prp2.360